The influence of Zn content on the microstructure and properties of die cast aluminum alloy (A380) was studied by regulating the Zn content. The Zn contents of the samples were 17.5 wt.%, 19.5 wt.%, and 21.5 wt.%, respectively. Engineering stress-strain curve, real stress-strain curve, and strain hardening rate curve at room temperature. After exceeding the yield point, the actual stress is significantly greater than the nominal stress, which is due to the assumption of material volume conservation during calculation. Therefore, this article uses strain hardening rate to characterize the uniform plastic deformation ability of the material. The research results indicate that with the increase of Zn content, the strength and plasticity of the alloy increase; Among them, the tensile strength increased from 240 MPa for A380 die cast aluminum alloy (as cast) to 320 MPa for Al Zn Si Cu alloy, with an increase of 35%; Based on the analysis of microstructure, it can be concluded that Zn element mainly dissolves in the Al matrix in aluminum alloy, playing a role in solid solution strengthening and improving the strength of the alloy.