Kinds of influencing factors in construction were considered, the seismic response spectrum analyses for whole cantilever construction were studied and compared with three long span typical continuous girder bridges, the vase-type solid pier, the thin-wall type rectangular hollow pier and the double-column type solid pier. The variation law of the seismic responses along with the construction stages was obtained and the comparison features were found out among the three bridges. The results show that the seismic internal force peaks mainly focus on the 6#, 8#, 9# girder segment, the side span closure and the deck construction stages. However the displacement peaks mainly appear at the 9# girder segment and the deck construction stage. The comparisons among the three bridges show that the bridge with the thin-wall type rectangular hollow pier has the maximum seismic stiffness in a great degree, the bridge with the double-column type solid pier takes second place and the bridge with the vase-type solid pier has the minimum stiffness. The seismic design should comprehensively consider the earthquake hazard in construction and multi-construction stages for the long span bridge constructed by the balanced cantilever method from the perspective of seismic safety and economy.