For study the relationship of coal and rock seepage properties between stress and fracture in cutting face, the self-developed coal-gas coupling and bidirectional loading system was used to conduct the change law of the large-sized coal and rock sample’s stress-fracture- seepage properties in Quasi-plane strain state. Test results indicate that the variation of different scale coal and rock sample’s stress-fracture-permeability have correlation and fractional characteristic. The seepage properties curve of three coal samples appear “saw-tooth”,which is not smooth phenomenon in the stage of pressure consolidation and elastic, the cause of this phenomenon is local buckling and the fractures develop from external to inward of coal sample in upload process. Different internal structure of sample leads to seepage properties transformation. Coal samples appear stress hysteresis. It is obvious of the rock sample brittle characteristic. The rock sample permeability emerges mutation and the largest moment of seepage velocity and the rupture time of rock are almost simultaneously.