The research object in this work was the 3 426 papers on the Web of Science from 2006 to 2015 about nanofabrication domain. A discussion was presented on the main mean and the core research area of nanofrication.By software Citespace III, the related basic research of this area was deeply analysed, the hot point and research front were clarified, the influential research units and representative scientists in nanofabrication from China and abroad were preliminary counted for providing basis on faster and better understanding the research present situation and progress of nanofabrication domain.